Roseanne would actually rank higher if she hadn't been so inactive until relatively recently. I vividly remember her first appearance on the Tonight Show - remember when appearing on the Tonight Show meant something?. She did a routine about the differences between a fat mom and a skinny mom. The main difference being, and I'm paraphrasing here, when you have a problem the skinny mom will try and get you to exercise and talk out your problems, something like that while the fat mom will bust out a gallon of ice cream and by the time you're done with your sugar-high, you've forgotten all about the problem.
Her television series, Roseanne, is still one of my favorite shows ever - a close third to Northern Exposure and Twin Peaks respectively - and thanks to syndication, I can still see it daily. The show is just now starting to get the respect it deserves. Roseanne herself made a good point on Larry King a few years back, the Roseanne show was the last of its kind. Since then there haven't really been any shows portraying blue-collar people, it's been replaced by the young, the rich, and the perceived rich - My Name is Earl being one of the few exceptions, but even that show, as great as it is, is built around the premise of the main characters winning on a lottery ticket.
A while back - a long while back - it was said that Roseanne secured the rights to develop an American version of AbFab. I'm not sure if that was true or not - although Patsy and Edina did show up on one episode of Roseanne once - but if she still has those rights, that's something I'd really like to see.